Editor in chief

Biomarker Insights is a peer-reviewed, open-access research journal where those engaged in biomarker research can turn for rapid communication of the latest advances in the application of biomarkers toward the discovery of new knowledge, and toward the clinical translation of that knowledge to increase the efficacy of practicing clinicians.

View factor

for journal

71692

Download PDF

(254.44 KB)

Request Reprints

Biomarker Discovery in Animal Health and Disease: The Application of Post-Genomic Technologies

Authors: Rowan E. Moore, Jennifer Kirwan, Mary K. Doherty and Phillip D. Whitfield

Publication Date: 10 Jul 2007

Biomarker Insights 2007:2 185-196

comments

Rowan E. Moore, Jennifer Kirwan, Mary K. Doherty and Phillip D. Whitfield

Proteomics and Functional Genomics Research Group, Faculty of Veterinary Science, University of Liverpool, Liverpool, United Kingdom.

Abstract: The causes of many important diseases in animals are complex and multifactorial, which present unique challenges. Biomarkers indicate the presence or extent of a biological process, which is directly linked to the clinical manifestations and outcome of a particular disease. Identifying biomarkers or biomarker profiles will be an important step towards disease characterization and management of disease in animals. The emergence of post-genomic technologies has led to the development of strategies aimed at identifying specific and sensitive biomarkers from the thousands of molecules present in a tissue or biological fluid. This review will summarize the current developments in biomarker discovery and will focus on the role of transcriptomics, proteomics and metabolomics in biomarker discovery for animal health and disease.

Categories: Genomics , Biomarkers

Keywords: Biomarker, Transcriptomics, Proteomics, Metabolomics, Veterinary.

Readers of this also read:

Biomarker Insights

Biomarker Discovery in Animal Health and Disease: The Application of Post-Genomic Technologies

Post comment