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Clinical Medicine Insights: Oncology

A Case of Metastatic Mucoepidermoid Carcinoma Complicated by Resistant Hypercalcemia

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Clinical Medicine Insights: Oncology 2011:5 83-87

Case report

Published on 17 Apr 2011

DOI: 10.4137/CMO.S5733


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Abstract

Tumors of salivary glands are uncommon and comprise of about 2%–4% of all head and neck tumors. About 75%–80% of these tumors are benign and include pleomorphic adenoma, monomorphic adenoma, oncocytoma, and papillary cystadenoma lymphomatosum. Mucoepidermoid carcinoma is the most common malignant tumor of salivary glands, representing 5–10% of all salivary gland tumors. Although known to be metastatic to local lymph nodes, distant metastases are rare (especially, with low and intermediate grade tumors). Histologic grade and the expression of various mucin glycoproteins are useful prognostic indicators. We present a case of mucoepidermoid carcinoma of parotid gland origin with distant metastases which is an uncommon occurrence with intermediate grade tumors. Also, this is the first reported case of humoral hypercalcemia of malignancy secondary to mucoepidermoid carcinoma.



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What Your Colleagues Say About Clinical Medicine Insights: Oncology
I am deeply obliged to the Editor in Chief of ‘Clinical Medicine Insights: Oncology’ for allowing us to publish our work in his journal.  Our manuscript went through a thorough and highly constructive peer review process that greatly increased its quality.  Additionally, we were positively surprised and satisfied by the editorial staff of Libertas Academica who worked hard to guide us through the publication process in a very smooth way.  They have all my personal ...
Dr Anna Koumarianou (Attikon University Hospital, Athens, Greece)
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