Bioinformatics and Biology Insights

Association of Putative Members to Family of Mosquito Odorant Binding Proteins: Scoring Scheme Using Fuzzy Functional Templates and Cys Residue Positions

Submit a Paper

Bioinformatics and Biology Insights 2013:7 231-251

Original Research

Published on 22 Jul 2013

DOI: 10.4137/BBI.S11096

Further metadata provided in PDF

Sign up for email alerts to receive notifications of new articles published in Bioinformatics and Biology Insights


Proteins may be related to each other very specifically as homologous subfamilies. Proteins can also be related to diverse proteins at the super family level. It has become highly important to characterize the existing sequence databases by their signatures to facilitate the function annotation of newly added sequences. The algorithm described here uses a scheme for the classification of odorant binding proteins on the basis of functional residues and Cys-pairing. The cysteine-based scoring scheme not only helps in unambiguously identifying families like odorant binding proteins (OBPs), but also aids in their classification at the subfamily level with reliable accuracy. The algorithm was also applied to yet another cysteine-rich family, where similar accuracy was observed that ensures the application of the protocol to other families.




BibTex citation   (BIBDESK, LATEX)


What Your Colleagues Say About Bioinformatics and Biology Insights
The publication of our paper in Bioinformatics and Biology Insights was highly professional and very pleasant on all levels: the guidelines for authors are concise, the online submission system is user-friendly, the comments from the reviewers were insightful and improved our paper, and the preparation of the manuscript for publication was efficient. I particularly liked the fast feedback from the staff on the state of the submission and review process.
Professor Werner Braun (Department of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, Texas, USA)
More Testimonials

Quick Links

New article and journal news notification services