To assess some simple blood parameters at birth that can be used as a basis to suspect α-thalassemia minor (ATM), a prospective study involving 202 consecutive neonates with MCV of less than 95 ﬂ or less were checked for Hb Barts by HPLC. The group was divided into two, one with an MCV of 90–95 (89 cases) and the other with an MCV below 90 (113 cases). For control, 104 consecutive neonates with an MCV 95 ﬂ were similarly checked. It has been confirmed that an MCV that is below 90 ﬂ, especially with and MCH of 30 pg is a strong indicator of the presence of ATM (109/113). On the other hand, MCV of 90 or more, especially with an MCH of 30 or more is a strong negative indicator for ATM (70/89). Firm diagnosis of ATM at birth can thus be secured in majority of neonates.
PDF (203.23 KB PDF FORMAT)
RIS citation (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)
BibTex citation (BIBDESK, LATEX)
My experience publishing in 'Clinical Medicine Insights: Oncology' was excellent. I was impressed with the quick review and proof-read processes. The electronic submission website is user friendly, and the continuous manuscript status updates received from the journal were helpful in tracking the progress of the paper.
All authors are surveyed after their articles are published. Authors are asked to rate their experience in a variety of areas, and their responses help us to monitor our performance. Presented here are their responses in some key areas. No 'poor' or 'very poor' responses were received; these are represented in the 'other' category.See Our Results
Copyright © 2014 Libertas Academica Ltd (except open access articles and accompanying metadata and supplementary files.)