Close
Help




JOURNAL

Clinical Medicine Insights: Geriatrics

HMGCoA-Reductase Inhibitors in Dementia: Benefit or Harm

Submit a Paper


Clinical Medicine Insights: Geriatrics 2009:3 13-22

Review

Published on 12 Jun 2009


Further metadata provided in PDF



Sign up for email alerts to receive notifications of new articles published in Clinical Medicine Insights: Geriatrics

Abstract

Dementia is a syndrome characterized by a decline in cognitive function. Alzheimer’s disease and cerebro-vascular disease are the most common causes of dementia. Many factors (genetic, life style, vascular etc.) appear to play some role in the development of dementia. Statins significantly reduce vascular disease and could reduce cognitive impairment in later life. Although most cross-sectional and longitudinal studies suggested a lower incidence of dementia in long-term statin users, randomized trials of statins in dementia did not slow disease progression. Furthermore, the effect of statins on cognitive performance is not well understood. Case reports suggest that statins may adversely affect cognition in some individuals, and prospective data studying the effects of statins in cognitively normal individuals is limited. Thus, the effects of statins on cognition in late life, remains uncertain.



Downloads

PDF  (628.22 KB PDF FORMAT)

RIS citation   (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)

BibTex citation   (BIBDESK, LATEX)




What Your Colleagues Say About Libertas Academica
The process of submission and publishing was a great experience.  During the few weeks from the submission to publication I have worked with high quality staff.  In my opinion, the easy communication was the most important characteristic of Libertas and an important influence on the final quality of the article.  I definitely recommend the publisher to my colleagues.
Dr Filomena Carvalho (Universidade de Sao Paulo, Sao Paulo, Brazil)
More Testimonials

Quick Links


New article and journal news notification services