Close
Help




JOURNAL

Clinical Medicine Insights: Geriatrics

38,665 Journal Article Views | Journal Analytics

HMGCoA-Reductase Inhibitors in Dementia: Benefit or Harm

Submit a Paper



Publication Date: 12 Jun 2009

Type: Review

Journal: Clinical Medicine Insights: Geriatrics

Citation: Clinical Medicine: Geriatrics 2009:3 13-22

Abstract

Dementia is a syndrome characterized by a decline in cognitive function. Alzheimer’s disease and cerebro-vascular disease are the most common causes of dementia. Many factors (genetic, life style, vascular etc.) appear to play some role in the development of dementia. Statins significantly reduce vascular disease and could reduce cognitive impairment in later life. Although most cross-sectional and longitudinal studies suggested a lower incidence of dementia in long-term statin users, randomized trials of statins in dementia did not slow disease progression. Furthermore, the effect of statins on cognitive performance is not well understood. Case reports suggest that statins may adversely affect cognition in some individuals, and prospective data studying the effects of statins in cognitively normal individuals is limited. Thus, the effects of statins on cognition in late life, remains uncertain.


Downloads

PDF  (628.22 KB PDF FORMAT)

RIS citation   (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)

BibTex citation   (BIBDESK, LATEX)






What Your Colleagues Say About Libertas Academica
This is my first publication with Libertas Academica. The whole process from submission to publication and responses were extremely rapid. The editorial staff informed me of the progress of the submission step by step. Thank you for your great service and kindness.
Dr Kazuyuki Karasuyama (Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan)
More Testimonials

Quick Links


New article and journal news notification services