Immunology
Open access articles on immunology. Articles from Immunology and Immunogenetics Insights, Immunotherapy Insights.
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- Prevalence and Prognostic Significance of Left Ventricular Dysfunction in Patients Presenting Acutely with Atrial Fibrillation
- Doxycycline in Clinical Medicine
- Early Involvement of Immune/Inflammatory Response Genes in Retinal Degeneration in DBA/2J Mice
- Collagen Racemization and Deposition in the Lungs of Aged Rats
- Design, Construction and Validation of Targeted BAC Array-Based CGH Test for Detecting the Most Commons Chromosomal Abnormalities
- An Investigation of Hair Cortisol Concentration Across Body Sites and within Hair Shaft
- Computational Identification and Characterization of Putative miRNAs in Nasonia Species
- A Novel Strategy for Mechanism Based Computational Drug Discovery
- Comparison of Two Output-Coding Strategies for Multi-Class Tumor Classification Using Gene Expression Data and Latent Variable Model as Binary Classifier
- Anti-inflammatory and Antihistaminic Study of a Unani Eye Drop Formulation
- Intractable Chronic Low-Back Pain Caused by Ligamentopathia Treated Using a Spinous Process Plate (S-plate)
- Intrabody-based Mapping of Latency-associated Nuclear Antigen from Kaposi’s Sarcoma-associated Herpesvirus Show Conserved Epitopes for Viral Latency Inhibition
- Evolution of Cellular Inclusions in Bietti’s Crystalline Dystrophy
- Inhibition of MLK3 Decreases Proliferation and Increases Antiproliferative Activity of Epidermal Growth Factor Receptor (EGFR) Inhibitor in Pancreatic Cancer Cell Lines
- Chondrodermatitis Nodularis Chronica Helicis
- Diurnal Variation in Peripheral (Hair) vs Central (Saliva) HPA Axis Cortisol Concentrations
- Accuracy of MSCT Coronary Angiography with 64 Row CT Scanner—Facing the Facts
- Gender Ratios in Autism, Asperger Syndrome and Autism Spectrum Disorder
- A Method to Detect Differential Gene Expression in Cross-Species Hybridization Experiments at Gene and Probe Level
- Hepatitis B Screening Compliance and Non-Compliance among Chinese, Koreans, Vietnamese and Cambodians
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- Intraspecific ITS Variability in the Kingdom Fungi as Expressed in the International Sequence Databases and Its Implications for Molecular Species Identification
- A Simple Derivation of the Distribution of Pairwise Local Protein Sequence Alignment Scores
- Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms
- DICOM Structured Reporting and Cancer Clinical Trials Results
- Mammoth and Elephant Phylogenetic Relationships: Mammut Americanum, the Missing Outgroup
- Evaluation of Two Outlier-Detection-Based Methods for Detecting Tissue-Selective Genes from Microarray Data
- Exploring the Evolutionary History of the Differentially Expressed Genes between Human Populations: Action of Recent Positive Selection
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- On the Adaptive Design Rules of Biochemical Networks in Evolution
- Phylogenetic diversity (PD) and biodiversity conservation: some bioinformatics challenges
- Fast Genes and Slow Clades: Comparative Rates of Molecular Evolution in Mammals
- Identification and Quantitation of Asparagine and Citrulline Using High-Performance Liquid Chromatography (HPLC)
- In Silico Promoter Analysis can Predict Genes of Functional Relevance in Cell Proliferation: Validation in a Colon Cancer Model
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Immunology and Immunogenetics Insights
Generalized Autoimmunity of ANCA and ASCA Related to Severity of Disease in Autistic Children with GI Disease (08/Oct/2009)
Aim: To assess serum Anti-Neutrophil cytoplasmic Antibody (ANCA—PR3 and MPO) and Anti-Saccharomyces Cerevisiæ Antibody (ASCA) levels in autistic children with severe gastrointestinal (GI) disease and to test the hypothesis that there is generalized autoimmunity in a subpopulation of autistic children with severe GI disease and that this autoimmunity is associated...
Dose-Specific Biphasic Effects of Simvastatin on the Expression of CXCL10 and CX3CL1 by Human Osteoblasts (17/Aug/2009)
Objective: To better understand the effects of simvastatin (SS) on the expression and secretion of two chemokines, CXCL10 and CX3CL1, by osteoblasts, and to test whether inhibition of isoprenoid intermediates of cholesterol biosynthesis were involved in the effects of SS. Methods: Human osteoblasts were incubated in the presence or absence of...
Aim: To assess both ant-PR3 and anti-MPO IgG anti-neutrophil cytoplasmic antibodies (ANCA), in autistic children with gastrointestinal symptoms and controls, and to test the hypothesis that there is an association between the presence of these antibodies and inflammatory GI disease seen in many autistic children. Subjects and Methods: ELISA’s were used...
Characteristics of Activated Monocyte Phenotype Support R5-Tropic Human Immunodeficiency Virus (10/Mar/2009)
Background: Microbial translocation has been recognized as an important factor in monocyte activation and contributing to AIDS pathogenesis with elevated plasma lipopolysaccharide (LPS) levels, as a marker for microbial translocation, seen in advanced HIV disease. Therefore, the current study was undertaken to assess monocyte activation in vitro by LPS...
Is the Adipose Tissue the Key Road to Inflammation? (17/Feb/2009)
It is now broadly accepted that white adipose tissue disorders, such as obesity, are associated with a chronic low-grade inflammation predisposing to the development of insulin-resistance, type 2 diabetes and cardiovascular complications. In obesity, accumulation of visceral adipose tissue, rather than subcutaneous adipose tissue, is regarded as the most critical...
Introductory Editorial by Dr Darren R Flower, The Jenner Institute, University of Oxford, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Headley Way, Headington, Oxford, U.K.
Immunotherapy Insights
Epstein-Barr virus (EBV)-associated malignancies offer a unique model to develop T cell-based immune therapies, targeting viral antigens expressed on tumor cells. Throughout the last 15 years, EBV-specific cytotoxic T-lymphocytes (CTL) have been successfully employed for the prophylaxis and treatment of EBV-related lymphoproliferative disorders (LPD) in immunocompromised hosts, particularly after hematopoietic...
Introductory Editorial (Immunotherapy Insights) (29/Jan/2009)
Introductory Editorial by Dr John Barrett, Allogeneic Stem Cell Transplantation, Bethesda, Maryland, U.S.A.