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Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine

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Pharmacotherapies for COPD

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Publication Date: 25 Apr 2013

Type: Review

Journal: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine

Citation: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine 2013:7 17-34

doi: 10.4137/CCRPM.S7211

Abstract

This review article summarizes the main treatments for chronic obstructive pulmonary disease, their mechanisms, and the key evidence from trials supporting their use. Drug classes covered were short acting beta agonists (SABA), short acting muscarinic antagonists (SAMA), long acting beta agonists (LABA), long acting antimuscarinics (LAMA), inhaled corticosteroids (ICS), LABA/ICS combinations, specific phosphodiesterase (PDE4) inhibitors, non-specific PDE inhibitors, mucolytics, and oxygen. Non-specific therapies, such as opiates for relief of dyspnoea and therapies for smoking cessation, are also covered briefly. For each class of drug, mechanisms of action are described, key clinical trial results are reported, and available agents compared. Finally, the place of each drug in therapy is compared between current worldwide guidelines.



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I had an excellent experience publishing our review article in Clinical Medicine Reviews.  The managing editor was very helpful and the process was very timely and transparent.
Professor Jonathan A. Bernstein (University of Cincinnati College of Medicine, Division of Immunology, Allergy Section, Cincinnati, OH, USA)
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