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Gene Regulation and Systems Biology

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Editor in Chief: James Willey

Aims & Scope: Gene Regulation and Systems Biology is concerned with the regulation of genes and the proteins they... more

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Processing Speed: Blind peer review by minimum of two expert reviewers and independent editorial decision within three to four weeks. Publication within average four weeks following acceptance.

ISSN: 1177-6250

H Index: 7 more info



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Endothelin-1 but not Endothelial Nitric Oxide Synthase Gene Polymorphism is Associated with Sickle Cell Disease in Africa (1092 Views since 25 May 2014)

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Species-Specific Regulation of t-PA and PAI-1 Gene Expression in Human and Rat Astrocytes (1344 Views since 08 May 2014)

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Overfeeding Dairy Cattle During Late-Pregnancy Alters Hepatic PPARα-Regulated Pathways Including Hepatokines: Impact on Metabolism and Peripheral Insulin Sensitivity (2271 Views since 03 Apr 2014)

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DNA Conformational Transitions Induced by Supercoiling Control Transcription in Chromatin (2172 Views since 12 Mar 2014)

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Tissue-Specific Gene Expression and Regulation in Liver and Muscle Following Chronic Corticosteroid Administration (1975 Views since 10 Mar 2014)

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Tetracycline Derivative Minocycline Inhibits Autophagy and Inflammation in Concanavalin-A-Activated Human Hepatoma Cells (1965 Views since 04 Mar 2014)

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Discovery of Emphysema Relevant Molecular Networks from an A/J Mouse Inhalation Study Using Reverse Engineering and Forward Simulation (REFS™) (1761 Views since 19 Feb 2014)

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Gene Expression and Gene Ontology Enrichment Analysis for H3K4me3 and H3K4me1 in Mouse Liver and Mouse Embryonic Stem Cell Using ChIP-Seq and RNA-Seq (2653 Views since 20 Jan 2014)

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Central Role of the PPARγ Gene Network in Coordinating Beef Cattle Intramuscular Adipogenesis in Response to Weaning Age and Nutrition (2338 Views since 08 Jan 2014)

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Innate Immunity Interactome Dynamics (3011 Views since 06 Jan 2014)

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Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases (7151 Views since 04 Nov 2013)

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CEBPG Exhibits Allele-Specific Expression in Human Bronchial Epithelial Cells (3642 Views since 04 Jul 2013)

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Dietary Lipid During Late-Pregnancy and Early-Lactation to Manipulate Metabolic and Inflammatory Gene Network Expression in Dairy Cattle Liver with a Focus on PPARs (4045 Views since 11 Jun 2013)

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Investigation of dmyc Promoter and Regulatory Regions (3709 Views since 15 May 2013)

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Yin Yang 1 and Adipogenic Gene Network Expression in Longissimus Muscle of Beef Cattle in Response to Nutritional Management (3799 Views since 16 Apr 2013)

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Butyrate Induced IGF2 Activation Correlated with Distinct Chromatin Signatures Due to Histone Modification (4362 Views since 26 Mar 2013)

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A Comprehensive Profile of ChIP-Seq-Based STAT1 Target Genes Suggests the Complexity of STAT1-Mediated Gene Regulatory Mechanisms (6338 Views since 26 Mar 2013)

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Global Consensus Theorem and Self-Organized Criticality: Unifying Principles for Understanding Self-Organization, Swarm Intelligence and Mechanisms of Carcinogenesis (4768 Views since 20 Feb 2013)

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Implications of Systemic Dysfunction for the Etiology of Malignancy (4106 Views since 06 Feb 2013)

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Extensive Ethnogenomic Diversity of Endothelial Nitric Oxide Synthase (eNOS) Polymorphisms (4021 Views since 15 Jan 2013)

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Effects of High Fat Feeding on Liver Gene Expression in Diabetic Goto-Kakizaki Rats (5489 Views since 28 Nov 2012)

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FOXO1 Up-Regulates Human L-selectin Expression Through Binding to a Consensus FOXO1 Motif (4711 Views since 29 Oct 2012)

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A Next-Generation Sequencing Approach to Study the Transcriptomic Changes During the Differentiation of Physarum at the Single-Cell Level (6399 Views since 01 Oct 2012)

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Ruminant Metabolic Systems Biology: Reconstruction and Integration of Transcriptome Dynamics Underlying Functional Responses of Tissues to Nutrition and Physiological Statea (9779 Views since 25 Jun 2012)

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Binding Motifs in Bacterial Gene Promoters Modulate Transcriptional Effects of Global Regulators CRP and ArcA (7639 Views since 30 May 2012)

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Quantification of Transcriptome Responses of the Rumen Epithelium to Butyrate Infusion using RNA-seq Technology (6168 Views since 16 May 2012)

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Unique Sex-Based Approach Identifies Transcriptomic Biomarkers Associated with Non-Syndromic Craniosynostosis (6073 Views since 16 May 2012)

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A Flexible and Qualitatively Stable Model for Cell Cycle Dynamics Including DNA Damage Effects (5589 Views since 11 Apr 2012)

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Regulatory Mechanisms in Bone Following Mechanical Loading (5637 Views since 17 Jan 2012)

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Identification of cis-Regulatory Elements in the dmyc Gene of Drosophila Melanogaster (7986 Views since 21 Dec 2011)

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Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNF-a) Induced Inflammatory Response in Bovine Cells (5726 Views since 05 Dec 2011)

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Biomolecular Self-Defense and Futility of High-Specificity Therapeutic Targeting (5855 Views since 21 Nov 2011)

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Application of Structure Equation Modeling for Inferring a Serial Transcriptional Regulation in Yeast (6160 Views since 10 Nov 2011)

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Developmental Regulation of Genes Encoding Universal Stress Proteins in Schistosoma mansoni (8023 Views since 19 Sep 2011)

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Identification of New SRF Binding Sites in Genes Modulated by SRF Over-Expression in Mouse Hearts (7525 Views since 12 Jul 2011)

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Critical Self-Organized Self-Sustained Oscillations in Large Regulatory Networks: Towards Understanding the Gene Expression Initiation (6893 Views since 22 Mar 2011)

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Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer) (11737 Views since 27 Feb 2011)

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Molecular Cloning of the Genes Encoding the PR55/Bβ/δ Regulatory Subunits for PP-2A and Analysis of Their Functions in Regulating Development of Goldfish, Carassius auratus (6391 Views since 20 Dec 2010)

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Identifying a Transcription Factor's Regulatory Targets from its Binding Targets (6577 Views since 08 Dec 2010)

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Alpha-Tocopherol Modulates Transcriptional Activities that Affect Essential Biological Processes in Bovine Cells (7013 Views since 22 Nov 2010)

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Overexpression of Colligin 2 in Glioma Vasculature is Associated with Overexpression of Heat Shock Factor 2 (6622 Views since 20 Oct 2010)

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Omega-6 Fat Supplementation Alters Lipogenic Gene Expression in Bovine Subcutaneous Adipose Tissue (7775 Views since 19 Oct 2010)

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HO1 mRNA and Protein do not Change in Parallel in Bronchial Biopsies of Patients After Long Term Exposure to Sulfur Mustard (6971 Views since 01 Oct 2010)

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Fractal Topology of Gene Promoter Networks at Phase Transitions (7484 Views since 28 Jul 2010)

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Do DNA Microarrays Tell the Story of Gene Expression? (7676 Views since 29 Jun 2010)

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Model-Based Analysis of FGF23 Regulation in Chronic Kidney Disease (7606 Views since 09 Jun 2010)

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GA-based Design Algorithms for the Robust Synthetic Genetic Oscillators with Prescribed Amplitude, Period and Phase (7372 Views since 24 May 2010)

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Inference of Cancer-specific Gene Regulatory Networks Using Soft Computing Rules (9309 Views since 31 Mar 2010)

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Transcriptional Response Of E. coli Upon FimH-mediated Fimbrial Adhesion (8368 Views since 24 Mar 2010)

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Microarray Data Analysis of Gene Expression Evolution (9603 Views since 27 Nov 2009)

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What Your Colleagues Say About Gene Regulation and Systems Biology
The reviewing and editorial management of our paper was timely, thorough, and systematic.  In particular the reviewers' comments resulted in a paper significantly more robust than the first version.
Dr Clark D Jeffries (University of North Carolina at Chapel Hill, Chapel Hill, NC, USA)
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